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Culture-Directed Infections
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Vertebral Osteomyelitis
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Enterobacterales
Enterobacterales
Therapy
Dose
Duration
Ceftriaxone
2g IV daily
6 weeks
or
Ciprofloxacin
500-750mg PO bid or
6 weeks
400mg IV q12h
Multi-drug resistant organism
Therapy
Dose
Duration
TMP/SMX
2 DS tabs PO bid
6 weeks
or
Meropenem
500mg IV q6h or
6 weeks
1g IV q8h
or
Ertapenem
1g IV daily
6 weeks