Gram negative organisms (excluding Pseudomonas and Stenotrophomonas)
| Empiric Therapy |
Intermittent Dosing 1 exchange daily with dwell time at least 6h |
Continuous Dosing (per each L bag) |
Duration |
|---|---|---|---|
| Based on C&S results: | |||
|
TMP/SMX |
1DS tab PO bid | 1DS tab PO bid |
21 days Strongly recommend catheter removal for refractory peritonitis. Treat for 14 days after catheter removal. |
| or | |||
| Ciprofloxacin |
500mg PO daily 750mg PO bid for CCPD |
50mg/L MD |
21 days Strongly recommend catheter removal for refractory peritonitis. Treat for 14 days after catheter removal. |
| or |
|
||
| Cefazolin IP | 15-20mg/kg once per day |
500mg/L LD then 125mg/L MD |
21 days Strongly recommend catheter removal for refractory peritonitis. Treat for 14 days after catheter removal. |
| or |
|
||
| Gentamicin IP | 0.6mg/kg once per day | Not advised |
21 days Strongly recommend catheter removal for refractory peritonitis. Treat for 14 days after catheter removal. |
CCPD = continuous cycling peritoneal dialysis
IP = intraperitoneally
LD = loading dose
MD = maintenance dose