Pseudomonas spp

Empiric Therapy

Intermittent Dosing

1 exchange daily with dwell time at least 6h

Continuous Dosing

(per each L bag)

Duration
Ceftazidime IP

3g loading dose then

1-1.5g once per day for long dwell

500mg/L LD then

125mg/L MD

21 days
If no response after 5 days, or associated with catheter-related infection, remove catheter. 

Treat for 14 days after catheter removal.

  Paediatric or short dwell: 20mg/kg once per day    
+      
[Tobramycin IP 0.6mg/kg once per day Not advised  
or      
Ciprofloxacin]

750mg PO daily

750mg PO bid for CCPD

50mg/L MD  

 

CCPD = continuous cycling peritoneal dialysis

IP = intraperitoneally

LD = loading dose

MD = maintenance dose