Empiric coverage of Candida spp not recommended unless yeast/Candida on Gram smear/culture AND at least one of below:
- yeast seen intracellularly or presence of pseudohyphae
- patient on immunosuppressive therapy
- multiple previous antibiotics
- upper GI tract perforation
- postoperative intra-abdominal infection
- recurrent intra-abdominal infection.
Add fluconazole if C. albicans, or an echinocandin (caspofungin or micafungin) if nonalbicans Candida spp.