Bacterial - Non-Contact Lens Wearer
- Risk factors:
- diabetes
- immunosuppression
- dry cornea.
- Quinolones may not provide optimal Staph and Strep coverage.
Usual Pathogens
Staphylococcus spp
Streptococcus spp
Bacillus cereus
Enterobacterales
Moraxella spp
H. influenzae
P. acnes
Ophthalmic Solutions
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Cefazolin 50mg/mL | q5min for first hour, then q15-60min, around the clock for 24-72 hours, then slowly reduce frequency | 3-4 weeks (dependent on clinical picture) |
| + | ||
| Tobramycin 14mg/mL | q5min for first hour, then q15-60min, around the clock for 24-72 hours, then slowly reduce frequency |
Alternative
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Vancomycin 50mg/mL | q5min for first hour, then q15-60min, around the clock for 24-72 hours, then slowly reduce frequency | 3-4 weeks (dependent on clinical picture) |
| + | ||
| Ceftazidime 50mg/mL | q5min for first hour, then q15-60min, around the clock for 24-72 hours, then slowly reduce frequency |