Pregnant

- Pre/1-week post treatment urine cultures recommended followed by monthly urine cultures during remainder of pregnancy.

- Quinolones are not recommended in pregnancy.

 
Usual Pathogens

E. coli
Other Enterobacterales
S. agalactiae (Group B Strep)
S. saprophyticus

 

Empiric Therapy Dose Duration
Nitrofurantoin Macrobid 100mg PO bid or 7 days
  50-100mg PO qid  
or    
Cephalexin 250-500mg PO qid 7 days
or    
Cefixime 400mg PO daily 7 days

Alternative

Empiric Therapy Dose Duration
TMP/SMX 1 DS tab PO bid 7 days