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Gemella spp

- Surgical intervention often required.

Penicillin MIC < 0.5µg/mL

Therapy	Dose	Duration
		Native	Prosthetic
Penicillin	4MU IV q4h	4 weeks	6 weeks
+
Gentamicin	3mg/kg IV daily	4 weeks	6 weeks

Penicillin MIC ≥ 0.5µg/mL

Therapy	Dose	Duration
		Native	Prosthetic
Ceftriaxone	2g IV daily	4 weeks	6 weeks
+
Gentamicin	3mg/kg IV daily	4 weeks	6 weeks

Penicillin and ceftriaxone MIC ≥ 4µg/mL or Severe penicillin/cephalosporin allergy

Therapy	Dose	Duration
		Native	Prosthetic
Vancomycin	15mg/kg IV q8-12h	4 weeks	6 weeks
+
Gentamicin	3mg/kg IV daily	4 weeks	6 weeks