Cronobacter sakazakii

  • formerly Enterobacter sakazakii

Gram Stain

  • Gram negative bacilli- fermenter

Clinical Significance

This organism is a food borne opportunistic pathogen found in spices, cereals/foodstuffs and has been associated with neonatal sepsis, necrotizing enterocolitis, bacteremia, meningitis, and brain abscesses. 

 

Usual Susceptibility Pattern

This organism produces an inducible cephalosporinase and should be considered resistant to penicillins and cephalosporins.

It is usually susceptible to carbapenems, TMP/SMX, aminoglycosides, and quinolones.

 

Empiric Therapy
Ciprofloxacin
or
TMP/SMX
Severe Infections:
Meropenem