Early onset (≤ 4 days hospitalization) or Late onset (> 4 days hospitalization)
- non-ICU
- no mechanical ventilation
- no broad-spectrum antibiotics
Usual PathogensS. pneumoniae
S. aureus/MRSA
H. influenzae
Enterobacterales
< 3 months old
Empiric Therapy |
Dose |
Duration |
Cefotaxime |
200mg/kg/d IV div q6h |
7 days |
≥ 3 months old
Empiric Therapy |
Dose |
Duration |
Ceftriaxone |
100mg/kg IV q24h |
7 days |
Empiric Therapy |
Dose |
Duration |
Vancomycin |
60mg/kg/d IV div q6h |
Minimum 14 days for confirmed MRSA |
or |
|
|
Linezolid |
< 5 years old: 30mg/kg/d IV/PO div q8h |
Minimum 14 days for confirmed MRSA |
|
> 5 years old: 20mg/kg/d IV/PO div q12h |
|