Empiric coverage of yeast/Candida spp not recommended unless yeast/Candida on Gram smear/culture AND at least one of below:
- yeast seen intracellularly or presence of pseudohyphae
- patient on immunosuppressive therapy
- multiple previous antibiotics
- upper GI tract perforation
- surgically treated pancreatitis
- recurrent intra-abdominal infection//bowel perforation
Add fluconazole if C. albicans, or an echinocandin (caspofungin or micafungin) if yeast species unknown.