ß-haemolytic Streptococci
- Early surgical intervention improves survival.
S. pyogenes (Group A)
| Therapy |
Dose |
Duration |
| |
|
Native |
Prosthetic |
| Penicillin |
3MU IV q4h |
4 weeks |
6 weeks |
| or |
|
|
|
| Ceftriaxone |
2g IV daily |
4 weeks |
6 weeks |
S. agalactiae (Group B), Streptococcus Group C,G
| Therapy |
Dose |
Duration |
| |
|
Native |
Prosthetic |
| [Penicillin |
4MU IV q4h |
4-6 weeks |
6 weeks |
| + |
|
|
|
| Gentamicin] |
3mg/kg IV daily |
2 weeks |
2 weeks |
| or |
|
|
|
| [Ceftriaxone |
2g IV daily |
4-6 weeks |
6 weeks |
| + |
|
|
|
| Gentamicin] |
3mg/kg IV daily |
2 weeks |
2 weeks |
Severe penicillin/cephalosporin allergy
| Therapy |
Dose |
Duration |
| |
|
Native |
Prosthetic |
| Vancomycin |
15mg/kg IV q8-12h |
4 weeks (4-6 weeks for Group B,C,G) |
6 weeks |
