Jugular Vein Septic Phlebitis (Lemierre's Syndrome)
- Suspect in teenagers/young adults with pharyngitis/fever and neck pain/swelling.
- May occur as a rare complication of otitis media, tonsillitis, or dental infections.
Usual Pathogens
Polymicrobial (1/3):
Oral anaerobes
Streptococcus spp
Empiric Therapy | Dose | Duration |
---|---|---|
Surgical drainage as appropriate | ||
+ | ||
Penicillin | 3-4MU IV q4h | 6-12 weeks |
+ | ||
Metronidazole | 500mg IV q8h |
Penicillin allergy
Empiric Therapy | Dose | Duration |
---|---|---|
Clindamycin | 600mg IV q8h | 6-12 weeks |
+ | ||
Metronidazole | 500mg IV q8h |