Late relapse or recurrent
- Late relapse or recurrence should be confirmed by culture.
- Consider:
- concurrent viral infection in a Group A Strep carrier
- new infections with Group A Strep.
- Continuous antibiotic prophylaxis is not recommended.
Usual Pathogens
Group A Streptococci
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Amoxicillin-clavulanate | 875mg PO bid | 10 days |
Alternative
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Azithromycin | 500mg PO daily | 3 days |
| or | ||
| Clarithromycin | 250mg PO bid | 10 days |
| or | ||
| Penicillin VK | 600mg PO bid or | 10 days |
| 300mg PO tid | ||
| or | ||
| Clindamycin | 300mg PO tid | 10 days |