Fungal
- Risk factors:
- trauma due to vegetation
- chronic topical steroid use.
- Very resistant to topical therapy; debridement usually required. May need corneal transplant.
- Topical/oral corticosteroids are contraindicated.
- Consider adjunctive systemic antifungal therapy.
Usual Pathogens
Aspergillus spp
Fusarium spp
Candida spp
Ophthalmic Solutions
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Voriconazole 1% | q1h, then slowly reduce frequency | Up to 6 weeks |
| or | ||
| Amphotericin B 0.15% | q2-3h, then slowly reduce frequency | Up to 6 weeks |
| or | ||
| Natamycin 5% | q2-3h, then slowly reduce frequency | Up to 6 weeks |