Operative vaginal delivery
Common Pathogens
Enterobacterales
Anaerobes
Group B Streptococci
Enterococcus spp
Regimen(s) of Choice See General Principles and Pre-Op Antibiotic Administration and Intraoperative Antibiotic Administration | ||
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Cefazolin | 2g IV | x 1 pre-op dose |
+ | ||
Metronidazole | 500mg PO | x 1 pre-op dose |
Alternative Regimens if allergy to cefazolin, or severe non-IgE-mediated reaction to any β-lactam (interstitial nephritis, hepatitis, hemolytic anemia, serum sickness, severe cutaneous reactions [e.g. SJS, TEN, DRESS]) | ||
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NB: Dosing prior to skin incision more effective than dosing after cord clamping. | ||
Gentamicin | 1.5mg/kg IV | x 1 pre-op dose |
+ | ||
Clindamycin | 600mg IV | x 1 pre-op dose |