Desired vancomycin trough is 10-20mg/L. Monitor renal function closely. See Vancomycin Dosing & Monitoring Guidelines.

Linezolid preferred over vancomycin if:

• MRSA with vancomycin MIC ≥ 1.5µg/mL

• concomitant nephrotoxic therapy

• pre-existing renal dysfunction.

Minimum 14 days for confirmed MRSA.