Bartonella spp
[European Heart J 2009;30:2369-2413.]
Clinical
B. quintana
- associated with alcoholism, homelessness, body lice.
B. henselae
- contact with cats, previous valvular disease
- valve surgery required in > 50% of patients
Diagnosis
-
Blood cultures – requires special blood culture media; only occasionally positive
-
Serology - antibody titre ≥ 1:800
-
Culture, immunohistology and PCR of surgical material
Therapy | Dose | Duration |
---|---|---|
Doxycycline | 100mg PO bid | 6 weeks |
+ | ||
Gentamicin | 3mg/kg IV daily or | 2 weeks |
1mg/kg IV q8h |