Lymphadenitis, infectious

Needs surgical consult for drainage of abscess if no improvement after 48 hours of antibiotic therapy. Bacterial, mycobacterial and fungal cultures recommended.

Acute

For complete list of infectious etiologies, see Recommended Empiric Therapy of Selected Infections in Adult Patients, Lymphadenitis

 
Usual Pathogens
Cervical

S. aureus
Group A Streptococci
Anaerobes 

 

Mild

Empiric Therapy Dose Duration
Cephalexin 40mg/kg/d PO div qid Until resolution of tenderness and fever (max 10 days)

Alternative

Empiric Therapy Dose Duration
Clindamycin 20-40mg/kg/d PO div qid Until resolution of tenderness and fever (max 10 days)

Moderate-severe

Empiric Therapy Dose Duration
Cefazolin 75mg/kg/d IV div q8h Until resolution of tenderness and fever (max 10 days)
or    
Clindamycin IV/PO 20-40mg/kg/d IV div q8h or Until resolution of tenderness and fever (max 10 days)
  20-40mg/kg/d PO div qid