Involving trunk, neck, head, extremity

Usual Pathogens

S. aureus/MRSA
Group A Streptococci

Mild

Temp ≤ 38.5°C and pulse ≤ 110/min
Empiric Therapy    
Local management
Antibiotics not generally recommended unless significant underlying conditions, e.g. obesity, wound overlying joint, immunosuppression.
   
 
Temp > 38.5°C or pulse > 110/min, or WBC > 12 x 109/L
Empiric Therapy Dose Duration
Cephalexin 40mg/kg/d PO div qid 24-48 hours

ß-lactam allergy

Empiric Therapy

Dose

Duration
Clindamycin 20mg/kg/d PO div qid 24-48 hours

Moderate-severe

Empiric Therapy

Dose

Duration
Cefazolin 75mg/kg/d IV div q8h 5-10 days

ß-lactam allergy/MRSA suspected

Empiric Therapy

Dose

Duration
Vancomycin 60mg/kg/d IV div q6h 5-10 days