Sexually transmitted
- For suspected sexually transmitted infection, combination therapy for both gonorrhea & chlamydia recommended.
Usual Pathogens
Chlamydia trachomatis
Neisseria gonorrhoeae
Mycoplasmoides genitalium (previously Mycoplasma genitalium)
Enterobacterales spp - in men who practice condomless insertive anal sex
Most likely caused by Chlamydia trachomatis and Neisseria gonorrhoeae
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Ceftriaxone | 250mg IM | 1 dose |
| + | ||
| Doxycycline | 100mg PO bid | 10-14 days |
Ceftriaxone allergy
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Levofloxacin | 500mg PO daily | 10 days |
Enterobacterales spp suspected/confirmed
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Ceftriaxone | 250mg IM | 1 dose |
| + | ||
| Levofloxacin | 500mg PO daily | 10 days |
Mycoplasma genitalium confirmed
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Moxifloxacin | 400mg PO daily | 14 days |