Shoulder arthroplasty, rotator cuff surgery
- For positive cultures, see Treatment of Culture-proven Prosthetic Joint Infections.
- Debridement of all necrotic tissue and removal of all nonabsorbable sutures and implants is recommended. Consider adding rifampin 300mg PO bid for Staph infections if hardware cannot be removed.
Usual Pathogens
C. acnes
S. aureus
Occasionally:
Polymicrobial
Empiric Therapy | Dose | Duration |
---|---|---|
Vancomycin | 15mg/kg IV q12h | 4-6 weeks |
Documented C. acnes infection
Empiric Therapy | Dose | Duration |
---|---|---|
Penicillin | 4MU IV q4h | 4-6 weeks |
or | ||
Ceftriaxone | 2g IV daily | 4-6 weeks |