Suppurative parotitis

- Complications include parapharyngeal infection.

 

Usual Pathogens

S. aureus

Mixed oral anaerobes in setting of debilitation, dehydration, or poor oral hygiene

 

Empiric Therapy

Dose

Duration
Amoxicillin-clavulanate 1.2g IV q8h 7-10 days
If MRSA risk factors, add:    
Vancomycin 15mg/kg IV q12h 7-10 days

Amoxicillin allergy

Empiric Therapy

Dose

Duration
Cefuroxime 1.5g IV q8h 7-10 days
+    
Metronidazole 500mg IV q12h  
If MRSA risk factors, add:    
Vancomycin 15mg/kg IV q12h 7-10 days

Amoxicillin and cefuroxime allergy

Empiric Therapy

Dose

Duration
Levofloxacin 750mg IV daily 7-10 days
+    
Metronidazole 500mg IV q12h  
If MRSA risk factors, add:    
Vancomycin 15mg/kg IV q12h 7-10 days