Lung abscess
- Careful assessment of risk factors recommended:
- dental/gingival disease
- immunosuppression
- immigration/travel history
- underlying lung disease.
- Consider TB/mycobacterial, fungal, parasitic etiology.
- Consider noninfectious etiology: malignancy, rheumatologic diseases, pulmonary emboli.
Polymicrobial including:
- Anaerobes
- S. anginosus group
- S. aureus/MRSA
- Enterobacterales
- S. pneumoniae
- Haemophilus spp
- Nocardia spp
- Legionella spp
| Empiric Therapy | Duration | |
|---|---|---|
| [Ceftriaxone | 1-2g IV daily | 3-6 weeks |
| + | ||
| Metronidazole] | 500mg IV/PO q12h | |
| or | ||
| Piperacillin-tazobactam | 3.375g IV q6h |
If MRSA suspected/documented, add:
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Vancomycin | 15mg/kg IV q8-12h | |
| or | ||
| Linezolid | 600mg IV/PO q12h |